Dr. Nate Daniels, a recently widowed husband who returns to South Africa, where he first met his wife, on a long-planned trip with their daughters to a game reserve managed by Martin Battles, an old family friend and wildlife biologist. But what begins as a journey of healing jolts into a fearsome fight for survival when a lion, a survivor of blood-thirsty poachers who now sees all humans as the enemy, begins stalking them.